Kv1.1 potassium channel Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26755-50, RA26755-100

Citations, Manuals and MSDS Available upon request.

Background: potassium voltage-gated channel subfamily A member 1 (KCNA1) Homo sapiens This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD) . The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK) . [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC 1:100-200

Alternative Names: KCNA1; Potassium voltage-gated channel subfamily A member 1; Voltage-gated K (+) channel HuKI; Voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1

Applications: IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 3736

Protein MW (KDa): 56

SWISS: Q09470

Source: Rabbit

Research Use Only